WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:negative regulation of cellular process       ID:GO:0048523
C=2840; O=25; E=9.51; R=2.63; rawP=6.88e-07; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
5  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
6  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
7  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
8  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
9  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
10  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
11  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
12  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
13  ENSG00000153208 NA MERTK c-mer proto-oncogene tyrosine kinase 10461 ENSG00000153208
14  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
15  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
16  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
17  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
18  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
19  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
20  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
21  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
22  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
23  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
24  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
25  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:negative regulation of biological process       ID:GO:0048519
C=3110; O=25; E=10.42; R=2.40; rawP=3.99e-06; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
5  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
6  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
7  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
8  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
9  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
10  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
11  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
12  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
13  ENSG00000153208 NA MERTK c-mer proto-oncogene tyrosine kinase 10461 ENSG00000153208
14  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
15  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
16  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
17  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
18  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
19  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
20  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
21  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
22  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
23  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
24  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
25  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:regulation of cellular process       ID:GO:0050794
C=7687; O=41; E=25.75; R=1.59; rawP=4.91e-06; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
3  ENSG00000166523 NA CLEC4E C-type lectin domain family 4, member E 26253 ENSG00000166523
4  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
5  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
8  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
9  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
10  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
11  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
12  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
13  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
14  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
15  ENSG00000153208 NA MERTK c-mer proto-oncogene tyrosine kinase 10461 ENSG00000153208
16  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
17  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
18  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
19  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
20  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
21  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
22  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
23  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
24  ENSG00000150048 NA CLEC1A C-type lectin domain family 1, member A 51267 ENSG00000150048
25  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052
26  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
27  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
28  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
29  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
30  ENSG00000131634 NA TMEM204 transmembrane protein 204 79652 ENSG00000131634
31  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
32  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
33  ENSG00000158445 NA KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 3745 ENSG00000158445
34  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
35  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
36  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
37  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
38  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
39  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
40  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263
41  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:regulation of multicellular organismal process       ID:GO:0051239
C=1772; O=17; E=5.93; R=2.86; rawP=3.43e-05; adjP=0.0047
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000166523 NA CLEC4E C-type lectin domain family 4, member E 26253 ENSG00000166523
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
5  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
6  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
7  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
8  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
9  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
10  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
11  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
12  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
13  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
14  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
15  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
16  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
17  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:regulation of biological process       ID:GO:0050789
C=8132; O=41; E=27.24; R=1.51; rawP=3.01e-05; adjP=0.0047
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
3  ENSG00000166523 NA CLEC4E C-type lectin domain family 4, member E 26253 ENSG00000166523
4  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
5  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
8  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
9  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
10  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
11  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
12  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
13  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
14  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
15  ENSG00000153208 NA MERTK c-mer proto-oncogene tyrosine kinase 10461 ENSG00000153208
16  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
17  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
18  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
19  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
20  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
21  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
22  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
23  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
24  ENSG00000150048 NA CLEC1A C-type lectin domain family 1, member A 51267 ENSG00000150048
25  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052
26  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
27  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
28  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
29  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
30  ENSG00000131634 NA TMEM204 transmembrane protein 204 79652 ENSG00000131634
31  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
32  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
33  ENSG00000158445 NA KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 3745 ENSG00000158445
34  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
35  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
36  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
37  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
38  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
39  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
40  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263
41  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:positive regulation of epithelial to mesenchymal transition       ID:GO:0010718
C=23; O=3; E=0.08; R=38.94; rawP=5.97e-05; adjP=0.0052
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
2  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
3  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646


Database:biological process       Name:negative regulation of intracellular protein kinase cascade       ID:GO:0010741
C=124; O=5; E=0.42; R=12.04; rawP=5.71e-05; adjP=0.0052
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
3  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209


Database:biological process       Name:regulation of multicellular organismal development       ID:GO:2000026
C=1098; O=13; E=3.68; R=3.53; rawP=4.58e-05; adjP=0.0052
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
6  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
7  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
8  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
9  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
10  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
11  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
12  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593
13  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:biological process       Name:regulation of developmental process       ID:GO:0050793
C=1436; O=14; E=4.81; R=2.91; rawP=0.0002; adjP=0.0060
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
6  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
7  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
8  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
9  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
10  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
11  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
12  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
13  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593
14  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:biological process       Name:regulation of macromolecule metabolic process       ID:GO:0060255
C=4151; O=26; E=13.90; R=1.87; rawP=0.0002; adjP=0.0060
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
5  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
6  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
7  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
8  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
9  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
10  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
11  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
12  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
13  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
14  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
15  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
16  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
17  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
18  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
19  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
20  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
21  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
22  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
23  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
24  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
25  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
26  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263


Database:molecular function       Name:transcription factor binding       ID:GO:0008134
C=432; O=9; E=1.50; R=6.01; rawP=1.56e-05; adjP=0.0019
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
6  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
7  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
8  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
9  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:molecular function       Name:E-box binding       ID:GO:0070888
C=28; O=3; E=0.10; R=30.90; rawP=0.0001; adjP=0.0060
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
3  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:molecular function       Name:protein kinase binding       ID:GO:0019901
C=361; O=6; E=1.25; R=4.79; rawP=0.0015; adjP=0.0500
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
3  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
4  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
5  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
6  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646


Database:molecular function       Name:RNA polymerase II regulatory region DNA binding       ID:GO:0001012
C=75; O=3; E=0.26; R=11.54; rawP=0.0022; adjP=0.0500
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
3  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:molecular function       Name:kinase binding       ID:GO:0019900
C=399; O=6; E=1.38; R=4.34; rawP=0.0025; adjP=0.0500
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
3  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
4  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
5  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
6  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646


Database:molecular function       Name:RNA polymerase II regulatory region sequence-specific DNA binding       ID:GO:0000977
C=73; O=3; E=0.25; R=11.85; rawP=0.0021; adjP=0.0500
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
3  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:molecular function       Name:protein binding transcription factor activity       ID:GO:0000988
C=497; O=6; E=1.72; R=3.48; rawP=0.0072; adjP=0.1234
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
3  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
4  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
5  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
6  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263


Database:molecular function       Name:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription       ID:GO:0001077
C=57; O=2; E=0.20; R=10.12; rawP=0.0167; adjP=0.1393
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
2  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016


Database:molecular function       Name:enzyme binding       ID:GO:0019899
C=1086; O=9; E=3.77; R=2.39; rawP=0.0116; adjP=0.1393
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
5  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
6  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
7  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
8  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
9  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:molecular function       Name:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription       ID:GO:0001228
C=61; O=2; E=0.21; R=9.45; rawP=0.0189; adjP=0.1393
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
2  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016


Database:cellular component       Name:nucleus       ID:GO:0005634
C=5955; O=32; E=18.86; R=1.70; rawP=0.0002; adjP=0.0154
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000173825 NA TIGD3 tigger transposable element derived 3 220359 ENSG00000173825
3  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
4  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
5  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
6  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
7  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
8  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
9  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
10  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
11  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
12  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
13  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
14  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
15  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
16  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
17  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
18  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
19  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
20  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
21  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
22  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
23  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
24  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
25  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
26  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
27  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
28  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
29  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
30  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
31  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
32  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263


Database:cellular component       Name:transcription factor complex       ID:GO:0005667
C=291; O=5; E=0.92; R=5.43; rawP=0.0022; adjP=0.0423
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
3  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
4  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
5  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:cellular component       Name:intracellular membrane-bounded organelle       ID:GO:0043231
C=9587; O=41; E=30.36; R=1.35; rawP=0.0021; adjP=0.0423
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
3  ENSG00000173825 NA TIGD3 tigger transposable element derived 3 220359 ENSG00000173825
4  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
5  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
8  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
9  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
10  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
11  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
12  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
13  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
14  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
15  ENSG00000178343 NA SHISA3 shisa homolog 3 (Xenopus laevis) 152573 ENSG00000178343
16  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
17  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
18  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
19  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
20  ENSG00000185432 NA METTL7A methyltransferase like 7A 25840 ENSG00000185432
21  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
22  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
23  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
24  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
25  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
26  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
27  ENSG00000127472 NA PLA2G5 phospholipase A2, group V 5322 ENSG00000127472
28  ENSG00000147642 NA SYBU syntabulin (syntaxin-interacting) 55638 ENSG00000147642
29  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
30  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
31  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
32  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
33  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
34  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
35  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
36  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
37  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
38  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
39  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
40  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
41  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263


Database:cellular component       Name:membrane-bounded organelle       ID:GO:0043227
C=9598; O=41; E=30.39; R=1.35; rawP=0.0022; adjP=0.0423
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
3  ENSG00000173825 NA TIGD3 tigger transposable element derived 3 220359 ENSG00000173825
4  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
5  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
8  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
9  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
10  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
11  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
12  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
13  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
14  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
15  ENSG00000178343 NA SHISA3 shisa homolog 3 (Xenopus laevis) 152573 ENSG00000178343
16  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
17  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
18  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
19  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
20  ENSG00000185432 NA METTL7A methyltransferase like 7A 25840 ENSG00000185432
21  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
22  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
23  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
24  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
25  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
26  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
27  ENSG00000127472 NA PLA2G5 phospholipase A2, group V 5322 ENSG00000127472
28  ENSG00000147642 NA SYBU syntabulin (syntaxin-interacting) 55638 ENSG00000147642
29  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
30  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
31  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
32  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
33  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
34  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
35  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
36  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
37  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
38  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
39  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
40  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
41  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263


Database:cellular component       Name:adherens junction       ID:GO:0005912
C=201; O=4; E=0.64; R=6.28; rawP=0.0037; adjP=0.0570
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
2  ENSG00000131634 NA TMEM204 transmembrane protein 204 79652 ENSG00000131634
3  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
4  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052


Database:cellular component       Name:anchoring junction       ID:GO:0070161
C=218; O=4; E=0.69; R=5.79; rawP=0.0050; adjP=0.0583
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
2  ENSG00000131634 NA TMEM204 transmembrane protein 204 79652 ENSG00000131634
3  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
4  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052


Database:cellular component       Name:intracellular       ID:GO:0005622
C=12564; O=48; E=39.79; R=1.21; rawP=0.0053; adjP=0.0583
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185340 NA GAS2L1 growth arrest-specific 2 like 1 10634 ENSG00000185340
2  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
3  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
4  ENSG00000173825 NA TIGD3 tigger transposable element derived 3 220359 ENSG00000173825
5  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
6  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
7  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
8  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
9  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
10  ENSG00000189266 NA PNRC2 proline-rich nuclear receptor coactivator 2 55629 ENSG00000189266
11  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
12  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
13  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
14  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
15  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
16  ENSG00000153208 NA MERTK c-mer proto-oncogene tyrosine kinase 10461 ENSG00000153208
17  ENSG00000178343 NA SHISA3 shisa homolog 3 (Xenopus laevis) 152573 ENSG00000178343
18  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
19  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
20  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
21  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
22  ENSG00000185432 NA METTL7A methyltransferase like 7A 25840 ENSG00000185432
23  ENSG00000099992 NA TBC1D10A TBC1 domain family, member 10A 83874 ENSG00000099992
24  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
25  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
26  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
27  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
28  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
29  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
30  ENSG00000150048 NA CLEC1A C-type lectin domain family 1, member A 51267 ENSG00000150048
31  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052
32  ENSG00000147642 NA SYBU syntabulin (syntaxin-interacting) 55638 ENSG00000147642
33  ENSG00000127472 NA PLA2G5 phospholipase A2, group V 5322 ENSG00000127472
34  ENSG00000102760 NA RGCC regulator of cell cycle 28984 ENSG00000102760
35  ENSG00000178199 NA ZC3H12D zinc finger CCCH-type containing 12D 340152 ENSG00000178199
36  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
37  ENSG00000224689 NA ZNF812 zinc finger protein 812 729648 ENSG00000224689
38  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
39  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
40  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
41  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
42  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
43  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
44  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
45  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
46  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
47  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263
48  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:cellular component       Name:cell-substrate adherens junction       ID:GO:0005924
C=136; O=3; E=0.43; R=6.97; rawP=0.0091; adjP=0.0779
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
2  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
3  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052


Database:cellular component       Name:focal adhesion       ID:GO:0005925
C=131; O=3; E=0.41; R=7.23; rawP=0.0083; adjP=0.0779
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
2  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
3  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052


Database:cellular component       Name:cell-substrate junction       ID:GO:0030055
C=143; O=3; E=0.45; R=6.63; rawP=0.0105; adjP=0.0783
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
2  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
3  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).